COVID-19 and Surface Disinfection: The Importance of the “Four C’s” of Disinfectants

With this context, we can look at the Four C’s of Disinfectants (Chemistry, Concentration, Contact Time, and Coverage) and why they’re important. When we talk about the first three, Chemistry, Concentration, and Contact Time, we really mean 1) what, 2) how much, and 3) how long it takes kill a specific pathogen. For example, the active ingredient in Clorox Healthcare Germicidal Bleach Wipes is 0.55% sodium hypochlorite and it claims a 3-minute contact time against C. difficile spores. In order to go to market, all disinfectants have to submit data to the EPA proving these claims.

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